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Cost International Projects National Projects Bilateral Scientific Cooperation Национални пројекти HORIZON-RIA ИДЕЈЕ позив

European Network for Neglected Vectors and Vector-Borne Infections

Project leader: Dr Andrei Mihalca

Project collaborators: Dr Snežana Tomanović, Dr Darko Mihaljica, Dr Ratko Sukara

Project number: TD1303

Duration of the project: 2013-2017

Leading Institution:

Description of the project:

Arthropod vectors and vector-borne diseases are frequently zoonotic infections and although their most significant clinical effects are often on the human population, the main infection sources are dependent on vectors, animal reservoirs and environmental factors. Hence, their surveillance and control require efficient and appropriately standardised methods, integrated knowledge and awareness among researchers, academic educators and policy-makers as well as well-trained young scientists. EurNegVec aims to promote all of these values and apply them in the field of vectors (ticks, mosquitoes, sandflies, midges and fleas) and vector-borne pathogens (viruses, bacteria, protozoa and nematodes). The main objectives are to endorse exchange of knowledge and methodologies, improve higher education, facilitate training of next generation experts, improve the European and national policies, produce innovation and disseminate the related scientific information, all these under the framework of the One Health paradigm.

Тип пројекта:

Cost

Epidemiological risk models for vector borne diseases in a changing world: The case study of mosquito and tick-borne diseases under different conditions of habitat integrity, environment and climate

Project leader: Prof dr Duško Ćirović and Dr Tizzani Paolo

Project collaborators: Dr Snežana Tomanović and Dr Darko Mihaljica

Project number:

Duration of the project: 2013-2015

Leading Institution: Faculty of Biology, University of Belgrade

Description of the project:

The principal goal of the project is to verify if, and to what extent, anthropic impact and climatic changes affect the risk of vector borne diseases transmission. The project aims to develop an epidemiological model where the environment is modeled on both italian and serbian characteristics, the wild animal host is the red fox, and the pathogens cause vector-borne diseases. The diseases considered are transmitted by mosquitos (Dirofilaria immitis), by ticks (Babesia sp. Ehrlichia sp., Anaplasma phagocitophylum), and by sandflies (Leishmania infantum). The pathogens to be studied were chosen because they are very different from the phylogenetic and biological points of view and in their ecological needs. In this way it will be possible to verify the large number of mechanisms through which environmental changes can affect the spread of pathogens.

Тип пројекта:

International Projects

Importance of wild canids as hosts and reservoirs for ticks and tick-borne pathogens in Austria and Serbia

Project leader: Dr Snežana Tomanović and Dr Georg Duscher

Project collaborators: Dr Snežana Tomanović, Dr Darko Mihaljica and Dr Ratko Sukara

Project number:

Duration of the project: 2016-2017

Leading Institution:Institute for Medical Research, University of Belgrade

Description of the project:

Identification of ticks and tick-borne diseases, as a growing problem in last decades, coincides with the increase of anthropogenic influence on biotic and abiotic components of ecosystems. As a result of direct and indirect anthropogenic impact, the migration of these pathogens to new areas is enabled. Wild canids are important hosts of ixodid ticks and recently they have been recognized as potential reservoirs of several tick-borne pathogens of zoonotic and domestic animals importance. The species like red foxes (Vulpes vulpes) and golden jackals (Canis aureus) also represent an important source of infections for domestic animals and humans, mostly due to their close proximity to human settlements and frequent exposure to different vector species. Currently, these populations are both still rapidly growing in urban areas and spreading their ranges toward Central and Eastern Europe increasing the risk of human and animal exposure to pathogens. However, many aspects of the epidemiology of tick-borne diseases in wild canids, such as host range, tick range and their geographical distribution are still poorly understood.

Тип пројекта:

International Projects

Enzootic transmission cycles of pathogenic microorganisms transmitted by ticks

Project leader: Dr Snežana Tomanović

Project collaborators:

Dr Snežana Tomanović, Dr Darko Mihaljica, Dr Ratko Sukara, Dr Gorana Veinović, and Dr Dragana Marković

Project number: OI173006

Duration of the project: 2011-2019

Leading Institution:

Institute for Medical Research, University of Belgrade

Description of the project:

In Europe, at least 6 agents of zoonotic vector-borne diseases have been identified in which ticks play an important role in transmission (Rickettsia sp., Anaplasma phagocytophilum, Borrelia burgdorferi sensu lato, Francisella tularensis, Crimean-Congo hemorrhagic fever virus, tick-borne encephalitis virus). Our preliminary investigations indicate the presence of A. phagocytophilum, F. tularensis, Rickettsia sp. and five genospecies of the B. burgdorferi complex in ixodid ticks in Serbia. According to epidemiological data, tick-borne encephalitis and Crimean-Congo hemorrhagic fever viruses are present in natural foci on the territory of Serbia, but no systematic studies on their presence in ticks have been performed so far. Research in this project included regular collection of material (ticks from vegetation and hosts, serum samples and host tissues), molecular detection of pathogens in samples, and cultivation, characterization and genotyping of these microorganisms. The research focused on potential natural hosts of these zoonotic diseases. The research results provided a clearer picture of the distribution, genetic diversity, and pathogenic potential of tick-borne microorganisms.

Тип пројекта:

National Projects

Toxoplasmosis in HSC transplant recipients: how to improve prevention at a reasonable cost?

Project leader:

from the Serbian side: Dr. Olgica Đurković-Đaković, from the French side: Prof. Florence Robert-Gangneux

Project collaborators:

dr Tijana Štajner, dr Jelena Srbljanović, Neda Bauman, Aleksandra Uzelac

Project number: /

Duration of the project: January 2018 – December 2019

Leading Institution: /

Description of the project:

Diagnosis and monitoring of reactivated toxoplasmosis (RT) in HSCT recipients was introduced into the transplantation practice in Serbia in 2013 (cooperation of the Mother and Child Health Care Institute and the NRL for toxoplasmosis). Despite its many benefits, clinical experience with this approach to control T. gondii infection in HSCT patients has also revealed gaps including diagnostic challenges pertinent for decisions on treatment, and lack of consensus on the frequency and duration of blood sample monitoring by qPCR after HSCT, respective of clinical setting and administration of prophylaxis. Thus, the goal of the proposed project is to, after standardization and harmonization of the qPCR protocol in both partner laboratories, identify subgroups of patients (according to the clinical setting, type of prophylaxis etc.) at the highest risk of RT, that would benefit the most from systematic PCR monitoring, with the final outcome to devise a cost-effective alternative for the prevention of RT after HSCT.

Тип пројекта:

International Projects