Projects

From Molecules to Brain Health: A Framework for European Excellence in Translational Neuroscience (BRAINFRAME)

Project leader: Dr. Inga Griskova Bulanova, Dr. Milica Zeković

Project collaborators: Dr. Jovana Bjekić, Dr. Uroš Konstantinović, Bojana Đukić, Marija Stanković, Milena Spoa, Dragana Stojić, Konstantin Tomić

Duration of the project: 2027-2031.

Leading institution: Vilnius University (Lithuania), Institute of Pharmacology of the Polish Academy of Sciences (Poland), Faculty of Medicine, University of Lisbon (Portugal), Barcelona Clinical Research Foundation – August Pi i Sunyer Biomedical Research Institute (Spain), Institute for Medical Research, University of Belgrade (Serbia), Karolinska Institutet (Sweden), SKEIN (Ukraine), UAB Orientos (Lithuania), Masaryk University (Czech Republic)

Description of the project:

BRAINFRAME aims to modernise and strengthen the research and innovation (R&I) dimension of the Institute for Medical Research (IMR) by establishing a sustainable, interconnected framework for excellence in translational neuroscience. The project bridges the entire translational continuum—from molecular and cellular discoveries through organoid and systems-level models to human validation and clinical practice. Within this integrated research environment, IMR leads specialized efforts in mechanistically oriented TES-EEG research, utilizing advanced neuromodulation and electrophysiological techniques to investigate the fundamental dynamics of brain health. BRAINFRAME promotes a culture of collaboration, focusing on the development of shared, FAIR-compliant protocols and AI-driven analytical pipelines to enhance research reproducibility and global competitiveness. BRAINFRAME acts as a coordination and support framework to bring translational neuroscience at IMR to a new level by partnering with leading European research institutions. The project will implement a comprehensive set of cooperation activities to strengthen scientific and administrative capacities, including structured researcher mobility schemes, cross-border expert training, and AI-governance workshops. By integrating molecular data with human-level neurophysiology, the consortium fosters an environment where researchers can develop advanced digital skills and implement responsible AI solutions. BRAINFRAME will generate substantial scientific and societal impact, reinforcing research careers and ensuring long-term institutional sustainability through open science practices and diverse knowledge-valorisation pathways.

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International Projects

Forecasting Depression Trajectories: Early Network-Guided Prediction of Severe and Persistent Disease Courses

Project leader: Dr. Jonathan Repple, Dr. Jovana Bjekić

Project collaborators: Dr. Uroš Konstantinović, Bojana Đukić, Marija Stanković, Milena Spoa, Dragana Stojić, Konstantin Tomić

Duration of the project: 2026-2031.

Leading institution: University of Frankfurt, Institute for Medical Research, University of Belgrade, Charité Berlin, UMC & VUMC Amsterdam, University Paris City, University Heidelberg, University of Melbourne, University of Hanoi

Description of the project:

FUTURE-D aims to redefine early detection and intervention strategies for individuals at risk of severe and persistent depression, positioning the Institute for Medical Research (IMR) as a leading hub within a prestigious international consortium. Moving beyond traditional symptom-based reaction, the project adopts a mechanism-informed prevention framework grounded in network science, dynamical systems, and control theory. Within this innovative program, IMR leads the delivery of precision TMS intervention for depression, utilizing advanced network control theory to calculate individualized, patient-specific stimulation targets. This approach shifts clinical practice from “one-target-fits-all” protocols to high-precision therapy that steers maladaptive brain connectivity back toward resilient configurations.
FUTURE-D serves as a crucial coordination and support tool for IMR to elevate its translational mental health research by partnering with leading global institutions across Germany, the Netherlands, France, and Australia. The project will facilitate the creation of scalable clinical decision-support tools and standardized neurostimulation workflows through a comprehensive set of cooperation activities, including structured mobility, expert training workshops, and intensive capacity-building boot-camps. These efforts will have a substantial scientific, technological, and societal impact, establishing a unique and equitable blueprint for implementing precision psychiatry within resource-constrained settings. To realize the project’s full potential, a wide array of communication, dissemination, and open-science measures will be implemented, ensuring long-term sustainability and policy translation in mental healthcare.

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International Projects

Development of the LIWCser Dictionary

Project leader: Dr. Jovana Bjekić

Project collaborators: Dr. Ljiljana Lazarević, Dr. Marko Živanović, Dr. Goran Knežević

Duration of the project: 2011-2012.

Leading institution: Institute for Medical Research, University of Belgrade

Description of the project:

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National Projects

Non-Invasive Modulation of Cortical Excitability and Plasticity – Non-Invasive Neuromodulation of the CNS in the Study of Physiological Mechanisms, Diagnosis and Treatment

Project leader: Dr. Saša Filipović

Project collaborators: Dr. Jovana Bjekić, Dr. Milan Jelić, Dr. Katarina Vulić, Dr. Uroš Konstantinović, Dr. Jasmina Vuksanović, Dunja Paunović

Project number: ON175012

Duration of the project: 2011-2019.

Leading institution: Institute for Medical Research, University of Belgrade

Description of the project:

Тип пројекта:

National Projects

NeuroShare: Sharing Tools and Expertise in Behavioral Neuroscience

Project leader: Dr. Andrea Vranić, Dr. Jovana Bjekić

Project collaborators: Dr. Jovana Bjekić

Project number: HR-1504-03-2223

Duration of the project: 2020-2024.

Leading institution: Institute of Psychology, University of Graz, Department of Psychology, Faculty of Cultural Sciences, University of Klagenfurt, Faculty of Philosophy, University of Sarajevo, Department of Psychology, Faculty of Humanities and Social Sciences, University of Rijeka, Faculty of Medicine, Masaryk University, Department of Physiotherapy, Professional Centre for Methodology and Healthcare, University of Miskolc, Faculty of Philosophy, University of Montenegro, Institute of Psychology, Jagiellonian University in Kraków, Department of Psychology, Faculty of Philosophy, University of Belgrade, Institute for Medical Research, University of Belgrade, Department of Psychology, Faculty of Philosophy, University of Novi Sad, Faculty of Arts, University of Ljubljana.

Description of the project:

The project is a mobility network aimed at exchange of knowledge and tools across cognitive neuroscientists and students at Univeristy of Zagreb and University of Rijeka (Croatia), University of Belgrade and University Novi Sad (Serbia), University of Klagenfurt (Austria), University of Sarajevo (BiH), Masaryk University (Czech Republic), University of Montenegro (Montenegro), University of Ljubljana (Slovenia) and Jagiellonian University (Poland).

Тип пројекта:

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Language Impairment in a Multilingual Society: Linguistic Patterns and the Road to Assessment

Project leader: Dr. Sharon Armon-Lotem, Dr. Jasmina Vuksanović

Project collaborators: Dr. Jovana Bjekić, Dr. Marko Živanović

Project number: IS0804

Duration of the project: 2012-2015.

Leading institution: Bar Ilan University, University of Amsterdam, University of Zagreb, University of Cyprus, Cyprus university of technology, Aalborg University, University of Oulu, University of Helsinki, University of Tours, François Rabelais University, Goethe-University, Aristotle University of Thessaloniki, Hungarian Research Centre for Linguistics, University College Cork, Tel Aviv University, University of Siena, University of Padova, Vytautas Magnus University, University of Luxembourg Campus Walferdange, University of Malta, University of Bergen, Bredtvet Resource Centre, University of Warsaw, Institute of Psychology – Jagiellonian University, Faculdade de Ciências Sociais e Humanas – Universidade Nova de Lisboa, Ministério da Educação /Gabinete do Secretário de Estado Adjunto e da Educação, Intercommunitary Development Association EURONEST / Asociatia de Dezvoltare Intercomunitara EURONEST, University „Al.I. Cuza”, Institute of Medical Research – University of Belgrade, Faculty of Education Bratislava, Presov University in Presov – Philosophical Faculty, Universitat Autònoma de Barcelona, University Jaume I Riu Sec, Lund University, Stockholm University, Bogazici university, Newcastle University, Istanbul Medipol University, University of Reading – Department of Clinical Language Sciences, School of Psychology & Clinical Language Sciences, University of Zagreb, Universitaire du Pont de Bois, Universite de tours, University of Education Heidelberg, University of Bremen, National and Kapodistrian University of Athens, Budapest University of Technology and Economics, National University of Ireland Galway, Vytautas Magnus University, Afdeling Neerlandistiek, Faculty of Psychology – Warsaw University, Skane University Hospital, St.Petersburg State Pediatric Medical University, Universite Saint Joseph, Academy of Albanian Studies – Institute of Linguistics and Literature, University of Minnesota, Arizona State University, Stellenbosch University, University of Alberta, The Promise Foundation

Description of the project:

Second language learners often produce language patterns resembling those of children with Specific Language Impairment (SLI). The overlap among the features of bilingual and impaired language lead to methodological and clinical confusion, which this Action aimed to resolve in order to improve language assessment. The project gathered scientist form over 20 countries to work within four main groups: WG1: Syntax and inferences with morphology and semantics; WG2 Narrative and discourse; WG3 Lexical and phonological processing; and WG 4 Executive functions. One of the major outcomes of the collaboration was the development of Cross-Linguistic Lexical Tasks (LITMUS – CLTs), that is now available in 15 languages.

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Pain Assessment in Patients with Impaired Cognition, Especially Dementia

Project leader: Dr. Stefan Lautenbacher

Project collaborators: Dr. Saša Filipović, Dr. Jovana Bjekić

Project number: TD1005

Duration of the project: 2011-2015.

Leading institution: University of Bamberg, LUMC, Cyclotron Research CentrenUniversite de Liege, Ghent University Hospital, University of Nicosia, Charles University Third Faculty of Medicine, Aarhus University Hospital, Faculty of Medicine, University Hospital, Clermont-Ferrand, France, University of Bamberg, National University of Ireland, Tel-Aviv University, Health Sciences Faculty, Israel, University of Turin and National Institute of Neuroscience, Academic Centre for Dentistry, University of BergenDepartment of Public Health and Primary Health Care, Clinical Hospital of Psychiatry, Medicine and Pharmacy University “Carol Davila”, Institute for Medical Research – University of Belgrade, Universitat Autònoma de Barcelona, Universitat Rovira i Virgili, University Hospital Geneva, University College London Research, University of Greenwich Centre of Positive Ageing, University of Liège, Aalborg University, University of Bamberg, Malteser Hospital, Tel aviv University, University of Torino, University of Turin, University of Bergen, University of Belgrade Faculty of Medicine, National Ageing Research Institute, RMIT University.

Description of the project:

The project was established to facilitate the development of a comprehensive and internationally agreed-on assessment toolkit for older adults targeting the various subtypes of dementia and various aspects of pain, including pain diagnostics, cognitive examination and guidelines for proper assessment. The collaboration created a clinical bedside tool for pain assessment in patients with dementia and cognitive impairments (PAIC). The PAIC tool is aimed to be adapted and validated for use across Europe in order to facilitate common research and to be used in clinical/health care settings.

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Collaboration of Aphasia Trialists (CATs)

Project leader: Dr. Marion Brody, Dr. Saša Filipović

Project collaborators: Dr. Jasmina Vuksanović, Dr. Jovana Bjekić, Dr. Marko Živanović

Project number: IS1208

Duration of the project: 2013-ongoing

Leading institution: Glasgow Caledonian University NMAHP Research Unit, Erasmus University Medical Centre, National and Kapodistrian University of Athens, Karolinska Institutet, University of Southern Denmark, Universtiy of Antwerp, University of Zagreb, University of Cyprus, University of Copenhagen, University of Tampere, Ecole Normale Superieure, University of Lille, University of Muenster, Freie Universitat Berlin, University of Oldenburg, Cyprus University of Technology, National and Kapodistrian University of Athens, Budapest University of Technology and Economics, Eötvös Loránd University, University of Limerick, Trinity College Dublin, Loewenstein Rehabilitation Hospital, Bar Ilan University, University of Venice ca’bembo, University of Verona, Vytautas Magnus University, University of Malta, University of Groningen, Statped sørøst, University of Oslo, University of Aveiro, University of Trento, Institute for Medical Research – University of Belgrade, Universitat Autònoma de Barcelona, University of Valencia, University of Gothenburg, University of Manchester, Charite Universitätsmedizin Berlin, University of PatrasMegalou Alexandrou, National and Kapodistrian University of Athens, University Of PatrasDepartment of Speech and Language Therapyt, Rijndam rehabilitation center, St.Petersburg State University, National Research University Higher School of Economics, St.Petersburg State Pediatric Medical University, The University of Queensland, University of the Witwatersrand, University of Canterbury

Description of the project:

The project seeks to improve our understanding of aphasia as it relates to predictors and prognosis, intervention effectiveness and social impact and re-integration for people with aphasia. It works to increase the availability and validity of multilingual assessments and outcome measures relating to aphasia. In this way the collaboration supports international research activities and increase the availability of clinical tools for people with aphasia who do not speak English and their healthcare professionals. The project gathered scientist form over 30 countries to work within six main groups: WG1 Aphasia Datasets; WG2 Aphasia assessment and outcomes; WG3 Prognosis and predictors of recovery; WG4 Effectiveness of interventions; WG5 Societal impact; W6 Cognition. One of the major outcomes so far has been the development of multilingual aphasia measurement instruments and recommendations for measurement of outcomes in adults with post-stroke aphasia (ROMA) within aphasia treatment studies.

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