This interdisciplinary project aimed to develop a new system of cold atmospheric plasma for use in biomedicine, environmental control, and nanotechnology. It consisted of four sub-projects: 1) Atmospheric discharges, 2) Plasma application in biology and medicine, 3) Plasma application in positron diagnostics, nanotechnology, and material functionalization, and 4) Measurements of biogenic volatile organic compounds. Institute for Medical Research participated in the second sub-project, led by Professor Pavle Milenković. Within this sub-project, the impact of cold atmospheric plasma on the regenerative properties of human dental-derived mesenchymal stromal/stem cells was investigated, both in vitro and in vivo (the rabbit calvarial critical-size defect model). The result of this sub-project was the publication of several papers in prestigious scientific journals and presentations at numerous international conferences.