Dr. Sanja Momčilović presented her lecture within the IMI’s series of scientific seminars

Published 15-07-2024

Dr. Sanja Momčilović, the research assistant from the Group for Neuroendocrinology at the Institute for Medical Research, delivered a lecture on July 12, 2024, titled “Mechanisms of interactions between mesenchymal stem cells and macrophages in the regulation of stress erythropoiesis,” featuring the key findings from her doctoral dissertation.

She specified the significance of specific signaling molecules in the interactions between macrophages and mesenchymal stem cells during stress erythropoiesis with the potential for new anemia treatment modalities.

“For the first time, it has been shown that NO and the purinergic signaling system play crucial roles in the communication between macrophages and mesenchymal stem cells under conditions of elevated glucocorticoid and erythropoietin concentrations. Understanding the functions of these signaling molecules in these interactions is crucial not only for elucidating the mechanisms that govern the accelerated proliferation and differentiation of immature erythroid cells during stress erythropoiesis but also for the potential development of new and more effective anemia treatments. This is particularly important given the risks of adverse effects from erythropoietin therapy, especially in oncology patients, and the increasing problem of resistance to existing erythropoiesis-stimulating agents.” dr. Sanja stated.

This lecture is part of a monthly scientific seminar series at the Institute for Medical Research, held in a hybrid format both in the Institute’s library and online. The series aims to introduce the scientific and academic community to the latest findings from research groups and to explore future study directions at IMI.

You can find Dr. Sanja Momčilović’s lecture, and all previously held seminars, on the Institute’s YouTube channel.

The next scientific seminar is due to take place on September 13, 2024.

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