Subproject: „Investigaton of the role of Thymus sepyllum L. and Urtica dioica active components in experimental models of cardiovascular diseases “, as a part of the project: „Development of new encapsulation and enzyme linked technologies for production of biocatalysts and biologically active food components to increase competitiveness, quality and safety “

Projects

Homepage / Projects / Subproject: „Investigaton of the role of Thymus sepyllum L. and Urtica dioica active components in experimental models of cardiovascular diseases “, as a part of the project: „Development of new encapsulation and enzyme linked technologies for production of biocatalysts and biologically active food components to increase competitiveness, quality and safety “

Project leader :Dr Nevena Mihailović-Stanojević

Project collaborators:

Dr Nevena Mihailović-Stanojević, dr Đurđica Jovović, dr Zoran Miloradović, dr Jelica Grujić Milanović, dr Milan Ivanov

Project number: III 46010

Duration of the project: 2011-2019

Leading Institution:

University of Belgrade, Institute for Medical Research, Institute of national importance for the Republic of Serbia

Description of the project:

The subproject was designed with the aim to explore the possible role of the active components of Thymus serpyllum L. and Urtica dioica L. from Serbia in the prevention and treatment of cardiovascular diseases. In this subproject, the in vivo effects of extracts of Thymus serpyllum L. and Urtica dioica L. on blood pressure, peripheral circulation resistance, lipid peroxidation, and oxidative stress were studied in the model of essential and malignant hypertension in rats with congenital hypertension. These results formed the basis for further research into the chronic effects of biologically active substances from Thymus serpyllum L. and Urtica dioica L. and for their application as dietary supplements in the therapy of cardiovascular diseases.